… Long-acting bronchodilators are recommended as maintenance therapy for chronic obstructive
pulmonary disease (COPD… to evaluate its potential as a novel treatment option in COPD. …

… -acting bronchodilators alone, and long-acting bronchodilators are … different classes of
bronchodilators can help achieve better … a singular long-acting β 2 -agonist/long-acting muscarinic …

… therapy in chronic obstructive pulmonary disease. The ICS/… compared to single long-acting
bronchodilator therapy. The … patients on single long-acting bronchodilator therapy or LABA/…

… of 2 long-acting bronchodilators in a pressurized metered-dose inhaler (MDI) is novel (see …
Unfortunately, it is well documented that 5%-18% (ie, several million) of COPD and asthma …

… by results from studies of patients with asthma, where compressive mechanical forces
that arise … with poor clinical outcomes in COPD: a novel phenotype. PLoS One 2012;7:e37483. …

… to show that novel treatments are … asthma-COPD overlap (ACO) should be abandoned
because it does not identify a clearly independent disease entity and rather indicates asthmatic …

… In addition, the study probably captured patients who also have asthma, which should have
… of COPD, the addition of a second long-acting bronchodilator as recommended by COPD …

… for COPD maintenance therapy based on COPD … Long-acting bronchodilators (with a
duration of action up to 24 h), such as long-acting muscarinic antagonists (LAMAs) and long-acting …

… antimuscarinic bronchodilator. AZD9164 was the first … program for a novel LAMA to treat
patients with COPD. AZD9164 is … mild persistent asthma and moderate to severe COPD and also …

… In addition, the overlap between asthma and chronic obstructive pulmonary disease (COPD)
has been increasingly recognised [4], with patients who demonstrate concomitant features …